Attributable Mortality of Candida Bloodstream Infections in the Modern Era: A Propensity Score Analysis.

ABSTRACT:

Background

This study quantifies the mortality attributable to Candida bloodstream infections (BSI) in the modern era of echinocandins.

Methods

We conducted a retrospective cohort study of adult patients admitted to Barnes Jewish Hospital, a 1368-bed tertiary care academic hospital, in Saint Louis, Missouri, from 1 February 2012 to 30 April 2019. We identified 626 adult patients with Candida BSI that were frequency-matched with 6269 control patients that had similar Candida BSI risk-factors. The 90-day all-cause mortality attributable to Candida BSI was calculated using three methods-propensity score matching, matching by inverse weighting of propensity score, and stratified analysis by quintile.

Results

The 90-day crude mortality was 42.4% (269 patients) for Candida

SUBMITTER: Mazi PB 

PROVIDER: S-EPMC10233239 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature