Direct brain recordings suggest a causal subsequent-memory effect.

ABSTRACT: Endogenous variation in brain state and stimulus-specific evoked activity can both contribute to successful encoding. Previous studies, however, have not clearly distinguished among these components. We address this question by analysing intracranial EEG recorded from epilepsy patients as they studied and subsequently recalled lists of words. We first trained classifiers to predict recall of either single items or entire lists and found that both classifiers exhibited similar performance. We found that list-level classifier output-a biomarker of successful encoding-tracked item presentation and recall events, despite having no information about the trial structure. Across widespread brain regions, decreased low- and increased high-frequency activity (HFA) marked successful encoding of both

SUBMITTER: Rubinstein DY 

PROVIDER: S-EPMC10233277 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature