Smoking Cessation and Changes in Anxiety and Depression in Adults With and Without Psychiatric Disorders.

ABSTRACT:

Importance

Although many people report a desire to quit smoking, concerns about mental health worsening after quitting are often raised by clinicians and people who smoke.

Objective

To assess changes in mental health following smoking cessation using 3 confirmatory coprimary analytical approaches.

Design, setting, and participants

This cohort study was conducted using data from a large, randomized clinical trial, the Evaluating Adverse Events in a Global Smoking Cessation Study. Analytical approaches included multivariable Tobit regression, propensity score adjustment, and instrumental variable regressions conducted from August to October 2022. Missing data were imputed for sensitivity analysis. The trial occurred in 16 countries at 140 centers between 2011 and 2015.

SUBMITTER: Wu AD 

PROVIDER: S-EPMC10233414 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature