Late-onset Cognitive Impairment and Modifiable Risk Factors in Adult Childhood Cancer Survivors.

ABSTRACT:

Importance

Long-term survivors of childhood cancer may be at elevated risk for new neurocognitive impairment and decline as they age into adulthood.

Objective

To determine whether aging adult childhood cancer survivors report more new-onset neurocognitive impairments compared with their siblings and to identify risk factors associated with such impairments.

Design, setting, and participants

Participants of this cohort study included adult survivors of childhood cancer from the Childhood Cancer Survivor Study and their siblings as a control group. The original cohort included survivors who received a diagnosis between January 1, 1970, and December 31, 1986, for whom longitudinal neurocognitive assessment was available. This study examined the prevalence of new-onset ne

SUBMITTER: Phillips NS 

PROVIDER: S-EPMC10233416 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature