Extracellular vesicles as a potential therapeutic for age-related macular degeneration.

ABSTRACT: Age-related macular degeneration is a major global cause of central visual impairment and severe vision loss. With an aging population, the already immense economic burden of costly anti-vascular endothelial growth factor treatment is likely to increase. In addition, current conventional treatment is only available for the late neovascular stage of age-related macular degeneration, and injections can come with potentially devastating complications, introducing the need for more economical and risk-free treatment. In recent years, exosomes, which are nano-sized extracellular vesicles of an endocytic origin, have shown immense potential as diagnostic biomarkers and in the therapeutic application, as they are bestowed with characteristics including an expansive cargo that closely resembles th

SUBMITTER: Chow LLC 

PROVIDER: S-EPMC10233781 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature