Comparison of therapies of white spot lesions: a systematic review and network meta-analysis.

ABSTRACT:

Objective

White spot lesions (WSLs), the earliest evidence of enamel demineralization, are considered amenable to intervention to achieve a remineralized or arrested state of caries. The management of WSLs is quite challenging, and there is no definitive cure as yet. We performed a network meta-analysis to assess the efficacy of seven therapies for WSLs and gave a hierarchy of them.

Materials and methods

We systematically searched the PubMed, EMBASE, Cochrane, and Web of Science databases (last search: July 2022) to identify all relevant studies. We limited our search to studies published in English. Randomized controlled designed in vitro/clinical trials related to the efficacy of the seven therapies for WSLs were included. Data extraction was performed independently by two

SUBMITTER: Xie Z 

PROVIDER: S-EPMC10233982 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature