Variation in mutation, recombination, and transposition rates in Drosophila melanogaster and Drosophila simulans.

ABSTRACT: The rates of mutation, recombination, and transposition are core parameters in models of evolution. They impact genetic diversity, responses to ongoing selection, and levels of genetic load. However, even for key evolutionary model species such as Drosophila melanogaster and Drosophila simulans, few estimates of these parameters are available, and we have little idea of how rates vary between individuals, sexes, or populations. Knowledge of this variation is fundamental for parameterizing models of genome evolution. Here, we provide direct estimates of mutation, recombination, and transposition rates and their variation in a West African and a European population of D. melanogaster and a European population of D. simulans Across 89 flies, we observe 58 single-nu

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10234296 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature