Evaluating increases in sensitivity from NORDIC for diverse fMRI acquisition strategies.

ABSTRACT: As the neuroimaging field moves towards detecting smaller effects at higher spatial resolutions, and faster sampling rates, there is increased attention given to the deleterious contribution of unstructured, thermal noise. Here, we critically evaluate the performance of a recently developed reconstruction method, termed NORDIC, for suppressing thermal noise using datasets acquired with various field strengths, voxel sizes, sampling rates, and task designs. Following minimal preprocessing, statistical activation (t-values) of NORDIC processed data was compared to the results obtained with alternative denoising methods. Additionally, we examined the consistency of the estimates of task responses at the single-voxel, single run level, using a finite impulse response (FIR) model. To examine th

SUBMITTER: Dowdle LT 

PROVIDER: S-EPMC10234612 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature