The development of functional connectivity within the dorsal striatum from early childhood to adulthood.

ABSTRACT: Dorsal striatum, principally comprising of caudate and putamen, is well-known to support motor function but also various higher-order cognitive functions. This is enabled by developing short- and long-range connections to distributed cortical regions throughout the life span, but few studies have examined developmental changes from young children to adults in the same cohort. Here we investigated the development of dorsal-striatal network in a large (n = 476), single-site sample of healthy subjects 3-42 years of age in three groups (children, adolescence, adults). The results showed that the connectivity within the striatum and to sensorimotor regions was established at an early stage of life and remained strong in adolescence, supporting that sensory-seeking behaviours and habit formation

SUBMITTER: Choi EJ 

PROVIDER: S-EPMC10236186 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature