Raster-scanning optoacoustic mesoscopy biomarkers for atopic dermatitis skin lesions.

ABSTRACT: Atopic dermatitis (AD) is the most common chronic inflammatory skin disease worldwide. Its severity is assessed using scores that rely on visual observation of the affected body surface area, the morphology of the lesions and subjective symptoms, like pruritus or insomnia. Ideally, such scores should be complemented by objective and accurate measurements of disease severity to standardize disease scoring in routine care and clinical trials. Recently, it was shown that raster-scanning optoacoustic mesoscopy (RSOM) can provide detailed three-dimensional images of skin inflammation processes that capture the most relevant features of their pathology. Moreover, precise RSOM biomarkers of inflammation have been identified for psoriasis. However, the objectivity and validity of such biomarkers i

SUBMITTER: Nau T 

PROVIDER: S-EPMC10236218 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature