Global, Race-Neutral Reference Equations and Pulmonary Function Test Interpretation.

ABSTRACT:

Importance

Race and ethnicity are routinely used to inform pulmonary function test (PFT) interpretation. However, there is no biological justification for such use, and it may reinforce health disparities.

Objective

To compare the PFT interpretations produced with race-neutral and race-specific equations.

Design, setting, and participants

In this cross-sectional study, race-neutral reference equations recently developed by the Global Lung Function Initiative (GLI) were used to interpret PFTs performed at an academic medical center between January 2010 and December 2020. The interpretations produced with these race-neutral reference equations were compared with those produced using the race and ethnicity-specific reference equations produced by GLI in 2012. The analysi

SUBMITTER: Moffett AT 

PROVIDER: S-EPMC10236239 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature