Radiomics for therapy-specific head and neck squamous cell carcinoma survival prognostication (part I).

ABSTRACT:

Background

Treatment plans for squamous cell carcinoma of the head and neck (SCCHN) are individually decided in tumor board meetings but some treatment decision-steps lack objective prognostic estimates. Our purpose was to explore the potential of radiomics for SCCHN therapy-specific survival prognostication and to increase the models' interpretability by ranking the features based on their predictive importance.

Methods

We included 157 SCCHN patients (male, 119; female, 38; mean age, 64.39 ± 10.71 years) with baseline head and neck CT between 09/2014 and 08/2020 in this retrospective study. Patients were stratified according to their treatment. Using independent training and test datasets with cross-validation and 100 iterations, we identified, ranked and inter-correlated p

SUBMITTER: Bernatz S 

PROVIDER: S-EPMC10236822 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature