Cooperation and competition between the default mode network and frontal parietal network in the elderly.

ABSTRACT: Recent research has shown that the Default Mode Network (DMN) typically exhibits increased activation during processing of social and personal information but shows deactivation during working memory (WM) tasks. Previously, we reported the Frontal Parietal Network (FPN) and DMN showed coactivation during task preparation whereas the DMN exhibited deactivation during task execution in working memory tasks. Aging research has shown that older adults exhibited decreased functional connectivity in the DMN relative to younger adults. Here, we investigated whether age-related cognitive decline is related to a reduced relationship between the FPN and DMN using a working memory task during the execution period. First, we replicated our previous finding that the FPN and DMN showed coactivation duri

SUBMITTER: Koshino H 

PROVIDER: S-EPMC10237017 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature