Genome-wide study of linkage disequilibrium, population structure, and inbreeding in Iranian indigenous sheep breeds.

ABSTRACT: Knowledge of linkage disequilibrium (LD), genetic structure and genetic diversity are some key parameters to study the breeding history of indigenous small ruminants. In this study, the OvineSNP50 Bead Chip array was used to estimate and compare LD, genetic diversity, effective population size (Ne) and genomic inbreeding in 186 individuals, from three Iranian indigenous sheep breeds consisting of Baluchi (n = 96), Lori-Bakhtiari (n = 47) and Zel (n = 47). The results of principal component analysis (PCA) revealed that all animals were allocated to the groups that they sampled and the admixture analysis revealed that the structure within the populations is best explained when separated into three groups (K  =  3). The average r2 values estimated between adjacent single nucleotide polymorphi

SUBMITTER: Barani S 

PROVIDER: S-EPMC10237446 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature