A smartphone-based tapping task as a marker of medication response in Parkinson's disease: a proof of concept study.

ABSTRACT: Tapping tasks have the potential to distinguish between ON-OFF fluctuations in Parkinson's disease (PD) possibly aiding assessment of medication status in e-diaries and research. This proof of concept study aims to assess the feasibility and accuracy of a smartphone-based tapping task (developed as part of the cloudUPDRS-project) to discriminate between ON-OFF used in the home setting without supervision. 32 PD patients performed the task before their first medication intake, followed by two test sessions after 1 and 3 h. Testing was repeated for 7 days. Index finger tapping between two targets was performed as fast as possible with each hand. Self-reported ON-OFF status was also indicated. Reminders were sent for testing and medication intake. We studied task compliance, objective perform

SUBMITTER: Broeder S 

PROVIDER: S-EPMC10237522 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature