Preoperative C-reactive protein-to-albumin ratio as a prognostic factor in biliary tract cancer: A systematic review and meta-analysis.

ABSTRACT:

Background

The preoperative C-reactive protein-to-albumin ratio is a novel inflammation-based prognostic marker in various cancers. However, its prognostic role in biliary tract cancer is unknown. We conducted a systematic review and meta-analysis to evaluate the prognostic value of preoperative C-reactive protein-to-albumin ratio in biliary tract cancer.

Methods

A systematic search of the literature for studies evaluating the prognostic value of C-reactive protein-to-albumin ratio in patients undergoing surgery for biliary tract cancer was conducted, and a random effects meta-analysis of overall survival and recurrence-free survival was performed.

Results

Nine studies with 1292 participants were included. The preoperative C-reactive protein-to-albumin ratio negativel

SUBMITTER: Utsumi M 

PROVIDER: S-EPMC10238051 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature