Effect of early mobilisation on long-term cognitive impairment in critical illness in the USA: a randomised controlled trial.

ABSTRACT:

Background

Patients who have received mechanical ventilation can have prolonged cognitive impairment for which there is no known treatment. We aimed to establish whether early mobilisation could reduce the rates of cognitive impairment and other aspects of disability 1 year after critical illness.

Methods

In this single-centre, parallel, randomised controlled trial, patients admitted to the adult medical-surgical intensive-care unit (ICU), at the University of Chicago (IL, USA), were recruited. Inclusion criteria were adult patients (aged ≥18 years) who were functionally independent and mechanically ventilated at baseline and within the first 96 h of mechanical ventilation, and expected to continue for at least 24 h. Patients were randomly assigned (1:1) via computer-generat

SUBMITTER: Patel BK 

PROVIDER: S-EPMC10238598 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature