Uromycobiome in infants and toddlers with and without urinary tract infections.

ABSTRACT:

Background

The bacterial components of the urobiome have been described in children, both with and without urinary tract infections (UTI). However, less is known about the pediatric uromycobiome: the community of fungi in the urine. The objectives of this study were to describe the uromycobiome in children and determine whether the uromycobiome differs between children with and without UTI.

Methods

This was a cross-sectional study of febrile children less than 3 years of age who presented to the Emergency Department and had a catheterized urine sample sent as part of clinical care. We obtained residual urine for use in this study and identified components of the uromyobiome through amplification and sequencing of the fungal ITS2 region. We then compared the uromycobiome betw

SUBMITTER: S Forster C 

PROVIDER: S-EPMC10238658 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature