Social relevance modulates multivariate neural representations of threat generalization in children and adults.

ABSTRACT: Few studies have examined threat generalization across development and no developmental studies have compared the generalization of social versus nonsocial threat, making it difficult to identify contextual factors that contribute to threat learning across development. The present study assessed youth and adults' multivoxel neural representations of social versus nonsocial threat stimuli. Twenty adults (M_age  = 25.7 ± 4.9) and 16 youth (M_age  = 14.1 ± 1.7) completed two conditioning and extinction recall paradigms: one social and one nonsocial paradigm. Three weeks after conditioning, participants underwent a functional magnetic resonance imaging extinction recall task that presented the extinguished threat cue (CS+), a safety cue (CS-), and generalization stimuli (GS

SUBMITTER: Glenn DE 

PROVIDER: S-EPMC10238918 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature