Upscaling vaccine manufacturing capacity - key bottlenecks and lessons learned.

ABSTRACT: The COVID-19 pandemic put enormous pressure on the vaccine production chain as billions of vaccines had to be produced in the shortest timeframe possible. Vaccine production chains struggled to keep up with demand, resulting in disruptions and production delays. This study aimed to make an inventory of challenges and opportunities that occurred in the production chain of the COVID-19 vaccine. Insights derived through approximately 80 interviews and roundtable discussions were combined with findings from a scoping literature review. Data were analysed through an inductive process where barriers and opportunities were linked to specific facets of the production chain. Key bottlenecks identified include a lack of manufacturing facilities, a lack of tech-transfer personnel, inefficient arrange

SUBMITTER: Feddema JJ 

PROVIDER: S-EPMC10239264 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature