Is artificial endometrial preparation more associated with early-onset or late-onset preeclampsia after frozen embryo transfer?

ABSTRACT:

Purpose

To explore whether the risks of early- or late-onset preeclampsia vary among frozen embryo transfer (FET) with different regimens for endometrial preparation and fresh embryo transfer (FreET).

Methods

We retrospectively included a total of 24129 women who achieved singleton delivery during their first cycles of in vitro fertilization (IVF) between January 2012 and March 2020. The risks of early- and late-onset preeclampsia after FET with endometrial preparation by natural ovulation cycles (FET-NC) or by artificial cycles (FET-AC) were compared to that after FreET.

Results

After adjustment via multivariable logistic regression, the total risk of preeclampsia was higher in the FET-AC group compared to the FreET group [2.2% vs. 0.9%; adjusted odds ratio (aOR): 2.

SUBMITTER: Niu Y 

PROVIDER: S-EPMC10239427 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature