Multi-compartmental MOF microreactors derived from Pickering double emulsions for chemo-enzymatic cascade catalysis.

ABSTRACT: Bioinspired multi-compartment architectures are desired in synthetic biology and metabolic engineering, as credited by their cell-like structures and intrinsic ability of assembling catalytic species for spatiotemporal control over cascade reactions like in living systems. Herein, we describe a general Pickering double emulsion-directed interfacial synthesis method for the fabrication of multicompartmental MOF microreactors. This approach employs multiple liquid-liquid interfaces as a controllable platform for the self-completing growth of dense MOF layers, enabling the microreactor with tailor-made inner architectures and selective permeability. Importantly, simultaneous encapsulation of incompatible functionalities, including hydrophilic enzyme and hydrophobic molecular catalyst, can be

SUBMITTER: Tian D 

PROVIDER: S-EPMC10239487 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature