Viable SARS-CoV-2 Omicron sub-variants isolated from autopsy tissues.

ABSTRACT:

Introduction

Pulmonary and extrapulmonary manifestations have been described after infection with SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19). The virus is known to persist in multiple organs due to its tropism for several tissues. However, previous reports were unable to provide definitive information about whether the virus is viable and transmissible. It has been hypothesized that the persisting reservoirs of SARS-CoV-2 in tissues could be one of the multiple potentially overlapping causes of long COVID.

Methods

In the present study, we investigated autopsy materials obtained from 21 cadaveric donors with documented first infection or reinfection at the time of death. The cases studied included recipients of different formulations of COVID-19 va

SUBMITTER: Maffia-Bizzozero S 

PROVIDER: S-EPMC10240073 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature