Analysis of the microbiota composition in the genital tract of infertile patients with chronic endometritis or endometrial polyps.

ABSTRACT:

Background

The previous researches show that infertile patients have a higher incidence of endometritis and endometrial polyps, and the occurrence of these two diseases is related to changes in the microbiota of the genital tract. We aim to determine the composition and changing characteristics of the microbiota in the genital tract (especially the endometrium) of infertile patients with chronic endometritis or endometrial polyps, and find the correlation between it and the occurrence of diseases.

Methods

This is a prospective study. We collected genital tract biopsy samples from 134 asymptomatic infertile patients receiving assisted reproductive therapy before embryo transfer. Through pathological examination and 16S ribosomal RNA(16S rRNA) sequencing, we determined the dis

SUBMITTER: Liang J 

PROVIDER: S-EPMC10240353 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature