Cardiac exposure in left-sided breast cancer patients undergoing deep inspiratory breath hold radiation therapy.

ABSTRACT:

Background

Left-sided breast cancer (BC) patients undergoing post-operative radiation therapy (PRT) may have higher risk of late cardiovascular toxicity, which may be reduced by hearth-sparing RT techniques. This study evaluated dosimetric parameters of the deep inspiration breath hold (DIBH) compared to free breathing (FB) RT. We analysed factors impacting on doses to the heart and cardiac substructures and sought anatomic factors allowing patient selection for DIBH.

Methods

The study group included 67 left-sided BC patients who underwent RT after breast-conserving surgery or mastectomy. Patients treated with DIBH were trained to hold their breath. Computed tomography (CT) scans were performed in both FB and DIBH patients. Plans were generated using 3-dimensional (3D) confo

SUBMITTER: Zhu H 

PROVIDER: S-EPMC10240437 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature