Effects of Early Emollient Use in Children at High Risk of Atopic Dermatitis: A German Pilot Study.

ABSTRACT: Several small studies have indicated that daily emollient use from birth might delay, suppress or prevent atopic dermatitis (AD). Two larger trials did not confirm this; however, a recent smaller study indicated a protective effect if daily emollient use is used in the first 2 months of life. Further research is needed to evaluate the effect of emollient use on development of AD. The current study randomly assigned 50 newborns who were at high risk of developing AD (1:1) to receive general infant skin-care advice (control group), or skin-care advice plus emollient with advice to apply emollient at least once daily until 1 year of age (intervention group). Repeated skin examinations, skin physiology measurements and skin microbiome profiling were performed. Of the children in the interventi

SUBMITTER: Harder I 

PROVIDER: S-EPMC10241252 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature