Safety and prognostic relevance of acetylcholine testing in patients with stable myocardial ischaemia or myocardial infarction and non-obstructive coronary arteries.

ABSTRACT:

Background

Intracoronary provocation testing with acetylcholine (ACh) is crucial for the diagnosis of functional coronary alterations in patients with suspected myocardial ischaemia and non-obstructive coronary arteries.

Aims

Our intention was to assess the safety and predictive value for major adverse cardiovascular and cerebrovascular events (MACCE) in patients presenting with ischaemia with non-obstructive coronary arteries (INOCA) or with myocardial infarction with non-obstructive coronary arteries (MINOCA).

Methods

We prospectively enrolled consecutive INOCA or MINOCA patients undergoing intracoronary ACh provocation testing.

Results

A total of 317 patients were enrolled: 174 (54.9%) with INOCA and 143 (45.1%) with MINOCA. Of these, 185 patients (58.4%) ha

SUBMITTER: Montone RA 

PROVIDER: S-EPMC10241282 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature