Risk and mortality of testicular cancer in patients with neurodevelopmental or other psychiatric disorders.

ABSTRACT:

Background

Both testicular germ cell tumours (TGCT) and neurodevelopmental disorders are associated with urogenital malformations. Few studies have investigated the association between psychiatric disorders and TGCT. We investigated whether history of any psychiatric or neurodevelopmental disorder is associated with increased risk or mortality of TGCT.

Method

This is a nested case-control study including 6166 TGCT patients diagnosed during 1992-2014, individually matched for age and calendar period to 61,660 controls. We calculated odds ratios (ORs) for the association between type of psychiatric diagnoses and TGCT risk. Among the cases, we used a cohort design and calculated hazard ratios (HRs) of the association between psychiatric diagnose and all-cause and TGCT-specific

SUBMITTER: Jansson AK 

PROVIDER: S-EPMC10241835 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature