Association of women-specific health factors in the severity of Parkinson's disease.

ABSTRACT: Parkinson's disease (PD) is an age-related neurological disorder known for the observational differences in its risk, progression, and severity between men and women. While estrogen has been considered to be a protective factor in the development of PD, there is little known about the role that fluctuations in hormones and immune responses from sex-specific health experiences have in the disease's development and severity. We sought to identify women-specific health experiences associated with PD severity, after adjusting for known PD factors, by developing and distributing a women-specific questionnaire across the United States and creating multivariable models for PD severity. We created a questionnaire that addresses women's specific experiences and their PD clinical history and deploye

SUBMITTER: Rao SC 

PROVIDER: S-EPMC10241917 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature