Molecular genetic positioning of small intestine and papilla of Vater carcinomas including clinicopathological classification.

ABSTRACT:

Background

Small intestine carcinoma (SIC) cases in Japan have recently been treated with chemotherapy according to colorectal carcinoma classification, while papilla of Vater carcinoma (PVC) cases according to cholangiocarcinoma (CHC) classification. However, few research reports support the molecular genetic validity of these therapeutic choices.

Patients and methods

Here, we investigated the clinicopathological and molecular genetic factors of SIC and PVC. We used the data from the Japanese version of The Cancer Genome Atlas. Additionally, molecular genetic data on gastric adenocarcinoma (GAD), colorectal adenocarcinoma (CRAD), pancreatic ductal adenocarcinoma (PDAC), and CHC were also referred to.

Results

This study consisted of tumor samples from 12 patients of S

SUBMITTER: Nakamura M 

PROVIDER: S-EPMC10242328 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature