Gender differences in juvenile systemic sclerosis patients: Results from the international juvenile scleroderma inception cohort.

ABSTRACT:

Objective

To compare organ involvement and disease severity between male and female patients with juvenile onset systemic sclerosis.

Methods

Demographics, organ involvement, laboratory evaluation, patient-reported outcomes and physician assessment variables were compared between male and female juvenile onset systemic sclerosis patients enrolled in the prospective international juvenile systemic sclerosis cohort at their baseline visit and after 12 months.

Results

One hundred and seventy-five juvenile onset systemic sclerosis patients were evaluated, 142 females and 33 males. Race, age of onset, disease duration, and disease subtypes (70% diffuse cutaneous) were similar between males and females. Active digital ulceration, very low body mass index, and tendon friction

SUBMITTER: Foeldvari I 

PROVIDER: S-EPMC10242693 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature