Osteosarcopenia predicts poor survival in patients with cirrhosis: a retrospective study.

ABSTRACT:

Background

Osteosarcopenia, defined as the coexistence of sarcopenia and osteoporosis, is associated with adverse clinical outcomes. The present study investigated the prognostic significance of osteosarcopenia in patients with cirrhosis.

Methods

This retrospective study evaluated 126 patients with cirrhosis. Participants were classified into three groups based on the presence or absence of (1) sarcopenia and/or osteoporosis; and (2) Child-Pugh (CP) class B/C cirrhosis and/or osteosarcopenia, and the cumulative survival rates were compared between the groups. Cox proportional hazards model was used to identify independent factors associated with mortality. Sarcopenia and osteoporosis were diagnosed according to the Japan Society of Hepatology and the World Health Organizatio

SUBMITTER: Saeki C 

PROVIDER: S-EPMC10242914 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature