Profiling Bartonella infection and its associated risk factors in shelter cats in Malaysia.

ABSTRACT:

Background

Poor disease management and irregular vector control could predispose sheltered animals to disease such as feline Bartonella infection, a vector-borne zoonotic disease primarily caused by Bartonella henselae.

Objectives

This study investigated the status of Bartonella infection in cats from eight (n = 8) shelters by molecular and serological approaches, profiling the CD4:CD8 ratio and the risk factors associated with Bartonella infection in shelter cats.

Methods

Bartonella deoxyribonucleic acid (DNA) was detected through polymerase chain reaction (PCR) targeting 16S-23S rRNA internal transcribed spacer gene, followed by DNA sequencing. Bartonella IgM and IgG antibody titre, CD4 and CD8 profiles were detected using i

SUBMITTER: Alias NNA 

PROVIDER: S-EPMC10244140 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature