Cortico-cortical feedback engages active dendrites in visual cortex.

ABSTRACT: Sensory processing in the neocortex requires both feedforward and feedback information flow between cortical areas¹. In feedback processing, higher-level representations provide contextual information to lower levels, and facilitate perceptual functions such as contour integration and figure-ground segmentation^2,3. However, we have limited understanding of the circuit and cellular mechanisms that mediate feedback influence. Here we use long-range all-optical connectivity mapping in mice to show that feedback influence from the lateromedial higher visual area (LM) to the primary visual cortex (V1) is spatially organized. When the source and target of feedback represent the same area of visual space, feedback is relatively suppressive. By contrast, when the source is of

SUBMITTER: Fisek M 

PROVIDER: S-EPMC10244179 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature