Case report: COVID-19-associated refractory thrombotic thrombocytopenic purpura complicated with Guillain-Barre syndrome.

ABSTRACT: Thrombotic thrombocytopenic purpura (TTP), a rare and lethal thrombotic microangiopathy, is an autoimmune disease that can be triggered by viral infections such as COVID-19. This condition is characterized by hemolytic microangiopathy, thrombocytopenia, and neurologic alterations, possibly accompanied by fever and renal damage. Moreover, more than 220 patients with Guillain-Barré syndrome (GBS) have been reported in association with the COVID-19 infection. In this report, we present a case of a patient who developed refractory TTP complicated by GBS following a SARS-CoV-2 infection. We aimed to highlight the importance of accurately diagnosing neurological complications associated with a COVID-19 infection and to demonstrate our strategies for treating a patient with COVID-19 infection-rel

SUBMITTER: Zhou R 

PROVIDER: S-EPMC10244661 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature