Acute stress alters recognition memory and AMPA/NMDA receptor subunits in a sex-dependent manner

ABSTRACT: Several studies have consistently reported a detrimental effect of chronic stress on recognition memory. However, the effects of acute stress on this cognitive ability have been poorly investigated. Moreover, despite well-documented sex differences in recognition memory observed in clinical studies, most of the preclinical studies in this field of research have been carried out by using solely male rodents. Here we tested the hypothesis that acute stress could affect the consolidation of different types of recognition memory in a sex-dependent manner. For this purpose, male and female C57BL6/J mice were exposed to 2-h of restrain stress immediately after the training session of both the novel object recognition (NOR) test and novel object location (NOL) tasks. Acute restraint stress did no

SUBMITTER: Torrisi S 

PROVIDER: S-EPMC10244889 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature