Berberine isolation from Coscinium fenestratum: optical, electrochemical, and computational studies† † Electronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3ra01769a

ABSTRACT: Berberine was extracted from Coscinium fenestratum (tree turmeric) and purified by column chromatography. The UV-Vis absorption spectroscopy of berberine was studied in acetonitrile and aqueous media. TD-DFT calculations employing the B3LYP functional were found to reproduce the general features of the absorption and emission spectra correctly. The electronic transitions to the first and second excited singlet states involve a transfer of electron density from the electron donating methylenedioxy phenyl ring to the electron accepting isoquinolium moiety. An estimate of the electrochemical gap (2.64 V) was obtained from microelectrode voltammetry and good agreement was found with quantum chemical calculations using the cc-pVTZ basis set and the B3LYP, CAM-B3LYP and wB97XD functionals. The c

SUBMITTER: Rajapakse R 

PROVIDER: S-EPMC10245225 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature