Hyperoxia in critically ill patients with sepsis and septic shock: a systematic review.

ABSTRACT:

Background

In septic patients, hyperoxia may help with its bactericidal effects, but it may cause systemic impairments. The role of hyperoxia and the appropriate oxygen target in these patients is unknown. The aim of this systematic review was to summarize the available literature.

Methods

We conducted a systematic search screening PubMed and Cochrane Library. Studies on adult patients with sepsis or septic shock and admitted to ICU addressing the topic of hyperoxia were included and described.

Results

We included 12 studies, for a total of 15.782 included patients. Five studies were randomized controlled trials (RCTs) or analyses from RCTs, three were prospective observational studies, and four were retrospective observational studies. The definition of hyperoxia was

SUBMITTER: Catalanotto FR 

PROVIDER: S-EPMC10245526 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature