Older Adults with Type 2 Diabetes Treated with Metformin: AME-MET Study - A Multicentric Real-world Study in Italy.

ABSTRACT:

Aims

Metformin is the most widely used drug for the first-line treatment of type 2 diabetes mellitus (T2DM), but its use and schedule have been poorly investigated in elderly patients.

Methods

We conducted an observational, cross-sectional, multicentric study on metformin in T2DM outpatients older than 65 years who were taking the drug for at least 6 months and referred to Italian Endocrinology and Diabetology Services. The primary endpoint was daily metformin dose, and secondary endpoints were the correlations between metformin dose and age, comorbidities, and concomitant use of other drugs. The study was open to all members of AME (Associazione Medici Endocrinologi).

Results

Fifteen Italian centers recruited 751 consecutive participants (42.9% older than 75 years, 4

SUBMITTER: Elena C 

PROVIDER: S-EPMC10245800 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature