Dosage-Adjusted Resistance Training in Mice with a Reduced Risk of Muscle Damage.

ABSTRACT: Progressive resistance training (PRT), which involves performing muscle contractions against progressively greater external loads, can increase muscle mass and strength in healthy individuals and in patient populations. There is a need for precision rehabilitation tools to test the safety and effectiveness of PRT to maintain and/or restore muscle mass and strength in preclinical studies on small and large animal models. The PRT methodology and device described in this article can be used to perform dosage-adjusted resistance training (DART). The DART device can be used as a standalone dynamometer to objectively assess the concentric contractile torque generated by the ankle dorsiflexors in mice or can be added to a pre-existing isokinetic dynamometry system. The DART device can be fabricat

SUBMITTER: Begam M 

PROVIDER: S-EPMC10246762 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature