External validation of the ISARIC 4C Mortality Score to predict in-hospital mortality among patients with COVID-19 in a Canadian intensive care unit: a single-centre historical cohort study.

ABSTRACT:

Purpose

With uncertain prognostic utility of existing predictive scoring systems for COVID-19-related illness, the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) 4C Mortality Score was developed by the International Severe Acute Respiratory and Emerging Infection Consortium as a COVID-19 mortality prediction tool. We sought to externally validate this score among critically ill patients admitted to an intensive care unit (ICU) with COVID-19 and compare its discrimination characteristics to that of the Acute Physiology and Chronic Health Evaluation (APACHE) II and Sequential Organ Failure Assessment (SOFA) scores.

Methods

We enrolled all consecutive patients admitted with COVID-19-associated respiratory failure between 5 March 2020 and 5 Mar

SUBMITTER: Vallipuram T 

PROVIDER: S-EPMC10247267 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature