Reported outcomes in transsphenoidal surgery for pituitary adenomas: a systematic review.

ABSTRACT:

Purpose

Transsphenoidal surgery is an established treatment for pituitary adenomas. We examined outcomes and time points following transsphenoidal surgery for pituitary adenoma to identify reporting heterogeneity within the literature.

Methods

A systematic review of studies that reported outcomes for transsphenoidal surgery for pituitary adenoma 1990-2021 were examined. The protocol was registered a priori and adhered to the PRISMA statement. Studies in English with > 10 patients (prospective) or > 500 patients (retrospective) were included.

Results

178 studies comprising 427,659 patients were included. 91 studies reported 2 or more adenoma pathologies within the same study; 53 studies reported a single pathology. The most common adenomas reported were growth hormone-

SUBMITTER: Layard Horsfall H 

PROVIDER: S-EPMC10247847 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature