Hepatic encephalopathy increases the risk for mortality and hospital readmission in decompensated cirrhotic patients: a prospective multicenter study.

ABSTRACT:

Introduction

Hepatic encephalopathy (HE) affects the survival and quality of life of patients with cirrhosis. However, longitudinal data on the clinical course after hospitalization for HE are lacking. The aim was to estimate mortality and risk for hospital readmission of cirrhotic patients hospitalized for HE.

Methods

We prospectively enrolled 112 consecutive cirrhotic patients hospitalized for HE (HE group) at 25 Italian referral centers. A cohort of 256 patients hospitalized for decompensated cirrhosis without HE served as controls (no HE group). After hospitalization for HE, patients were followed-up for 12 months until death or liver transplant (LT).

Results

During follow-up, 34 patients (30.4%) died and 15 patients (13.4%) underwent LT in the HE group, while 60

SUBMITTER: Riggio O 

PROVIDER: S-EPMC10248517 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature