GWAS in tetraploid potato: identification and validation of SNP markers associated with glycoalkaloid content.

ABSTRACT: Genome-wide association studies (GWAS) are a useful tool to unravel the genetic architecture of complex traits, but the results can be difficult to interpret. Population structure, genetic heterogeneity, and rare alleles easily result in false positive or false negative associations. This paper describes the analysis of a GWAS panel combined with three bi-parental mapping populations to validate GWAS results, using phenotypic data for steroidal glycoalkaloid (SGA) accumulation and the ratio (SGR) between the two major glycoalkaloids α-solanine and α-chaconine in potato tubers. SGAs are secondary metabolites in the Solanaceae family, functional as a defence against various pests and pathogens and in high quantities toxic for humans. With GWAS, we identified five quantitative trait lo

SUBMITTER: Vos PG 

PROVIDER: S-EPMC10248624 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature