Reclassification of Pre-Heart Failure Stages Using Cardiac Biomarkers: The ARIC Study.

ABSTRACT:

Background

The recent heart failure (HF) guideline recommends the inclusion of cardiac biomarkers in defining Stage B HF.

Objectives

The authors evaluated the impact of incorporating cardiac biomarkers to reclassify HF in 5,324 participants (mean age: 75.8 years) without prevalent HF enrolled in the ARIC (Atherosclerosis Risk In Communities) study and assessed prognosis of Stage B using cardiac biomarkers.

Methods

Using N-terminal pro-B-type natriuretic peptide (<125 pg/mL or ≥125 pg/mL), high-sensitivity troponin T (<14 ng/L or ≥14 ng/L), and abnormal cardiac structure/function by echocardiography, individuals were classified as Stage A_new and Stage B_new HF, respectively. Stage B_new was further evaluated as elevated biomarker only, ab

SUBMITTER: Jia X 

PROVIDER: S-EPMC10248756 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature