Effects of alcohol use on sperm chromatin structure, a retrospective analysis.

ABSTRACT:

Background

The evaluation of the infertile couple is often complex as multiple factors in both the male and female can contribute, including social history. Previous studies have displayed that male ethanol consumption can disturb sperm motility, nuclear maturity, and deoxyribonucleic acid (DNA) integrity. The main purpose of this study is to evaluate the effects of male alcohol use on sperm chromatin structure analysis (SCSA®). This study was a retrospective chart review of 209 couples that presented to a midsize infertility clinic in the Midwest and had a semen analysis and SCSA® performed. Data extracted from the electronic medical record included demographics, tobacco use, alcohol use, occupational exposures, semen analysis results, and SCSA® results (DNA Fragmentation index (D

SUBMITTER: Trautman A 

PROVIDER: S-EPMC10249235 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature