Circulating Galectin-3 levels and Diabetic Nephropathy: a systematic review and meta-analysis.

ABSTRACT:

Aims

Changes of serum galectin-3 (Gal-3) is associated with the pathogenesis of diabetic nephropathy (DN). However, current literature indicates that the given results remain debatable and inconsistent. Hence, the aim of this present meta-analysis was to focus on the predictive role of serum Gal-3 in patients with DN.

Methods

The PubMed, Embase, Cochrane Library and Web of Science databases were systematically searched for studies that reported the relationship between Gal-3 levels and DN risk, from the inception of each database to March, 2023. The literature we selected for inclusion based on inclusion and exclusion criteria. The standard mean difference (SMD) with corresponding 95% confidence intervals (95% CI) were used to investigate the association. When I²

SUBMITTER: Yong G 

PROVIDER: S-EPMC10249253 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature