Interfacial Behavior of Cubosomes: Combined Langmuir-Blodgett/Langmuir-Schaefer and AFM Investigations.

ABSTRACT: The Langmuir technique was applied for the first time to compare the layers obtained by spreading lipid liquid-crystalline nanoparticles monoolein 1-oleoyl-rac-glycerol (GMO)/Pluronic F108 cubosomes with the monolayers obtained by mixing the same components in chloroform at the air-water interface. The differences in the monolayer behavior and in the acting intermolecular forces were examined. The similarity of the isotherms obtained for the mixed components system and the cubosome-derived layer proved the disintegration of cubosomes into a single monolayer upon contact with the air-water interface. Despite the low Pluronic F108 content in both types of layers, a strong structural role of this stabilizer was also demonstrated. Cubosome-derived systems supported on hydrophilic mica substrat

SUBMITTER: Zaborowska M 

PROVIDER: S-EPMC10249408 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature