Temporal proteomic profiling reveals functional pathways in vaccinia virus-induced cell migration

ABSTRACT:

Introduction

Viral diseases have always been intricate and persistent issues throughout the world and there is a lack of holistic discoveries regarding the molecular dysregulations of virus-host interactions. The temporal proteomics strategy can identify various differentially expressed proteins and offer collaborated interaction networks under pathological conditions.

Method

Herein, temporal proteomics at various hours post infection of Vero cells were launched to uncover molecular alternations during vaccinia virus (VACV)-induced cell migration. Different stages of infection were included to differentiate gene ontologies and critical pathways at specific time points of infection via bioinformatics.

Results

Bioinformatic results showed functional and distinct on

SUBMITTER: Lu J 

PROVIDER: S-EPMC10249495 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature