Missing data approaches in longitudinal studies of aging: A case example using the National Health and Aging Trends Study.

ABSTRACT:

Purpose

Missing data is a key methodological consideration in longitudinal studies of aging. We described missing data challenges and potential methodological solutions using a case example describing five-year frailty state transitions in a cohort of older adults.

Methods

We used longitudinal data from the National Health and Aging Trends Study, a nationally-representative cohort of Medicare beneficiaries. We assessed the five components of the Fried frailty phenotype and classified frailty based on their number of components (robust: 0, prefrail: 1-2, frail: 3-5). One-, two-, and five-year frailty state transitions were defined as movements between frailty states or death. Missing frailty components were imputed using hot deck imputation. Inverse probability weights were u

SUBMITTER: Duchesneau ED 

PROVIDER: S-EPMC10249888 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature